Microsystems Laboratory 4 (LMIS4)

The Laboratory of Prof. Philippe Renaud is doing research in BioMEMS, microfluidics, nanofluidics and bioelectronic implants. Research on basic nanofluidic phenomena is used for understanding molecular transport in nanochannels. Our current focus is on applications in microsystems for handling, analysis and culture of biological cells.

The LMIS4 Laboratory is going to close at the end of 2022, at the time of the retirement of Prof. Renaud.

Work done by Clémentine Lipp, PhD student

Large array of vertical hydrodynamic single cell traps connected to buried microfluidic channels (by Clémentine Lipp)

 

What we focus on

• We have studied novel methods in flow cytometry and cell sorting based on electrical impedance analysis and dielectric properties of the cells. • We also develop micro-bioreactors for on-chip co-culture of cells in drug screening and toxicology applications. • We are developing devices for bioelectronic implants such as micro-electrodes for neural recordings and stimulation, biomechanical sensors for eye pressure or articular implants. • Our group has been involved in the valorization of research by creation of several start-up companies.

La vidéo présente un oscillateur microfluidique opérant en flux laminaire et dont les oscillations résultent de l’interaction de deux jets de liquide qui se font face (by Arnaud Bertsch)
Les oscillations apparaissent alors qu’il n’y a aucune variation des flux d’entrée, ce qui est tout à fait inhabituel en microfluidique.
Grâce à une collaboration avec le Laboratoire de Mécanique des Fluides et Instabilités dirigé par François Gallaire, ce comportement des fluides a pu être simulé